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OCR: GIP is a forty-two amino-acid peptide th testinal produced by K cells in the upper small i bit gastric mucosa. It was originally thought to int this secretions (gastric inhibitory peptide), b + proved to be a pharmacological action. / of the physiological doses, GIP is a component nsulin enteroinsular axis, stimulating prandial known as release, Such insulin-releasing factors ar arly of 'incretins'. Thus, food ingestion, particu s the carbohydrate and long-chain fatty acids, stimulus for GIP secretion. family of In common with other members of this id and peptides, it inhibits secretion of gastric a e effects stimulates insulin release, although the occur only at pharmacological doses.